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KMID : 0360220090500060864
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Journal of the Korean Ophthalmological Society
2009 Volume.50 No. 6 p.864 ~ p.869
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The Effect of Posterior Subtenon Triamcinolone Injection in Panretinal Photocoagulation Induced Visual Dysfunction of Diabetic Retinopathy
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Hwang Hyung-Bin
Park Young-Hoon
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Abstract
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Purpose: To evaluate the efficacy of a prophylactic posterior sub-Tenon’s capsule injection of Triamcinolone acetonide (TA) against macular edema and visual dysfunction by panretinal photocoagulation (PRP) in patients with severe nonproliferative and proliferative diabetic retinopathy.
Methods: Thirty-eight eyes of 19 patients who have diabetic retinopathy without macular edema and whose retinopathy was bilateral and symmetrical were evaluated. Triamcinolone was injected into the posterior sub-Tenon’s capsule in one eye of the patients and nothing was injected in the other eye as a control. Two weeks later, PRP was performed every other week for 4 sessions on both eyes in all patients. The clinical course of visual acuity and macular edema was monitored for up to approximately 6 months after the initial PRP.
Results: There was no statistically significant difference of visual acuity before PRP in the 2 groups (p＞0.05), and there was no macular edema in any patient. For a follow-up period of 6 months, visual dysfunction was more severe in the TA-injected eye than the control. However, the difference was not statistically significant (p＞0.05) throughout the follow-up period except at the 20-week time point. On the other hand, macular edema occurred in 2 eyes (10.5%) of the TA-injected group, and in 4 eyes (21.1%) of the control group. IOP elevation as a complication caused by TA-injection occurred in 2 eyes (10.5%). However, IOP was controlled successfully by anti-glaucomatic eye drops.
Conclusions: Posterior sub-Tenon’s capsule injection of Triamcinolone is a safe and effective treatment modality for preventing PRP-induced visual dysfunction and macular edema.
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KEYWORD
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Panretinal photocoagulation, Posterior sub-Tenon’s capsule injection of Triamcinolone acetonide
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